Allergy and immunology is the management, diagnosis, treatment of disorders that relate to the immune system. These conditions range from the very common to the very rare, spanning all ages and and can involve various organ systems.
- HLA-B*58:01 and Risk of Allopurinol-Induced Severe Cutaneous Adverse Reactions in the USon October 29, 2025
This genetic association study examined human leukocyte antigen (HLA) class I and II in a cohort of US patients who received a diagnosis of allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis or drug reaction with eosinophilia and systemic symptoms compared with allopurinol-tolerant and population control participants.
- Red Papulonodules in a Kidney Transplant Recipienton October 29, 2025
A man in his 60s who had a kidney transplant was taking mycophenolate mofetil, tacrolimus, and prednisone presented with painless lesions on the left upper extremity. What is your diagnosis?
- Topical Anti-Inflammatory Treatmentsf Atopic Dermatitison October 29, 2025
This clinical evidence synopsis summarizes findings from a 2024 Cochrane systematic review and network meta-analysis of topical anti-inflammatory treatments for atopic dermatitis.
- Pediatric JAK Inhibitor Use and Height in Common Inflammatory Diseaseson October 29, 2025
This cohort study evaluates the association between Janus kinase (JAK) inhibitor use and height in pediatric patients with atopic dermatitis, juvenile idiopathic arthritis, and inflammatory bowel disease.
- Active Rash, Interstitial Lung Disease, and Neutrophil to Lymphocyte Ratio and Mortality in Dermatomyositison October 29, 2025
This cohort study assesses the clinical and laboratory markers associated with in-hospital mortality in patients with dermatomyositis.
- Pediatric JAK Inhibitor Use and Height in Common Inflammatory Diseaseson October 29, 2025
This cohort study evaluates the association between Janus kinase (JAK) inhibitor use and height in pediatric patients with atopic dermatitis, juvenile idiopathic arthritis, and inflammatory bowel disease.
- Topical Anti-Inflammatory Treatmentsf Atopic Dermatitison October 29, 2025
This clinical evidence synopsis summarizes findings from a 2024 Cochrane systematic review and network meta-analysis of topical anti-inflammatory treatments for atopic dermatitis.
- Active Rash, Interstitial Lung Disease, and Neutrophil to Lymphocyte Ratio and Mortality in Dermatomyositison October 29, 2025
This cohort study assesses the clinical and laboratory markers associated with in-hospital mortality in patients with dermatomyositis.
- Topical Anti-Inflammatory Treatmentsf Atopic Dermatitison October 29, 2025
This clinical evidence synopsis summarizes findings from a 2024 Cochrane systematic review and network meta-analysis of topical anti-inflammatory treatments for atopic dermatitis.
- Updated COVID-19 Vaccine Generates Strong Immune Responseon October 28, 2025
Topline data indicate that the 2025-2026 LP.8.1-adapted monovalent COVID-19 vaccine, marketed as Comirnaty, elicits a robust immune response.
- Equity, Diversity, and Inclusion Concerns From JAMA Network Peer Reviewerson October 28, 2025
This cross-sectional study evaluates JAMA Network peer reviewers’ use of the equity, diversity, and inclusion concerns checkbox and used JAMA Dermatology as a case study to categorize concerns described in confidential comments.
- Pink Papules and Plaqueson October 28, 2025
A 2-month-old boy had multiple annular, pink papules and plaques with hyperpigmentation and desquamation on the scalp, palms, and soles; physical examination and ultrasound revealed hepatosplenomegaly, and aspartate and alanine aminotransferase levels were elevated. What is the diagnosis and what would you do next?
- Cancer Risk in Psoriasis Treated With Adalimumab, Secukinumab, or Ustekinumabon October 22, 2025
This cohort study estimates 5-year standardized risks for any first cancer among patients being treated with biologics for moderate to severe psoriasis.
- Lamellar Ichthyosis Improvement With Acitretin and Dupilumabon October 22, 2025
This case report describes 2 siblings in their 20s with lamellar ichthyosis.
- Mediterranean Diet May Offer Psoriasis Benefitson October 10, 2025
Extra virgin olive oil, plant-based foods, and moderate meat consumption may help with psoriasis, according to a recent study published in JAMA Dermatology. The randomized clinical trial found that a 16-week Mediterranean diet reduced psoriasis severity, possibly due to anti-inflammatory benefits. Current psoriasis dietary advice focuses on weight loss for patients who are overweight, but these findings suggest an option for all patients.
- Diagnostic Utility of Initial Cardiac Screening in Patients With Cutaneous Sarcoidosison September 17, 2025
This cross-sectional study examines the diagnostic performance of electrocardiogram, review of systems, or both in detecting cardiac sarcoidosis.
- Overtime and Agency Nurse Staffing and Impacts on Patient Safetyon April 2, 2025
Health Policy
- Increased Utilization of Overtime and Agency Nurses and Patient Safetyon April 2, 2025
This quality improvement study examines the association between overtime and agency nurse staffing hours and hospital patient safety at 70 US hospitals from 2019 to 2022.
- Hospital-Acquired Pressure Ulcers in Patients With Acute Cervical Spinal Cord Injuryon December 6, 2024
This cohort study evaluates whether pressure ulcers acquired during initial hospitalization are associated with neurological and functional long-term outcome and survival among patients with spinal cord injuries.
