In this issue of JAMA Pediatrics, Copeland et al report on a 20-year follow-up of children, now adults, who were part of a natural experiment of cash transfers to some families. Due to an opening of a casino on the tribal lands located in the southeastern US, which coincided with an ongoing longitudinal cohort study of families called the Great Smoky Mountains Study, a coincidence allowed the study of outcomes of children receiving an exogenous income supplement compared with those who did not. This ongoing study helped address a long-standing and important question: Can investments in families early in the life course lead to better outcomes, especially for children living in poverty?
Clinical Practice Guidelines