In Reply We thank Bhurawala for their comments regarding heterogeneity in the Network Meta-Analysis of Trials of Initial Oxygen in Preterm Newborns (NETMOTION) study. Their letter highlights the importance of examining potential sources of heterogeneity when considering the clinical implications of the finding that high initial fractional inspired oxygen (FiO2) may reduce mortality in preterm infants compared to low or intermediate levels.
Clinical Practice Guidelines